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Si-Meng Chen Selected Research

4- (2- (dimethylamino)vinyl)- 2- (3- hydroxyphenyl)- 6- morpholinopyrimidine- 5- carbonitrile

9/2010WJD008, a dual phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin inhibitor, prevents PI3K signaling and inhibits the proliferation of transformed cells with oncogenic PI3K mutant.

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Si-Meng Chen Research Topics

Disease

3Breast Neoplasms (Breast Cancer)
08/2018 - 11/2014
3Neoplasms (Cancer)
01/2012 - 09/2010
2Carcinoma (Carcinomatosis)
04/2012 - 01/2012
1Hernia (Hernias)
01/2020
1Stomach Neoplasms (Stomach Cancer)
04/2012
1Colorectal Neoplasms (Colorectal Cancer)
12/2011

Drug/Important Bio-Agent (IBA)

3Phosphotransferases (Kinase)IBA
01/2017 - 09/2010
2(5- (2,4- bis((3S)- 3- methylmorpholin- 4- yl)pyrido(2,3- d)pyrimidin- 7- yl)- 2- methoxyphenyl)methanolIBA
08/2018 - 11/2014
2Proteins (Proteins, Gene)FDA Link
11/2014 - 01/2012
2TOR Serine-Threonine KinasesIBA
04/2012 - 09/2010
2artemisinin (artemisinine)IBA
01/2012 - 12/2011
2Pharmaceutical PreparationsIBA
01/2012 - 09/2010
2artenimol (dihydroartemisinin)IBA
01/2012 - 12/2011
1Estrogen ReceptorsIBA
08/2018
1TamoxifenFDA LinkGeneric
08/2018
1Biomarkers (Surrogate Marker)IBA
01/2017
1AlpelisibIBA
01/2017
1tyrosine receptor (receptor, tyrosine)IBA
01/2017
1Drug CombinationsIBA
11/2014
15- (2,4- dihydroxy- 5- isopropylphenyl)- 4- (4- morpholin- 4- ylmethylphenyl)isoxazole- 3- carboxylic acid ethylamideIBA
11/2014
1MTOR InhibitorsIBA
11/2014
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
11/2014
1DNA (Deoxyribonucleic Acid)IBA
11/2014
1LigandsIBA
04/2012
1CXC ChemokinesIBA
04/2012
1Sirolimus (Rapamycin)FDA Link
04/2012
1AnnexinsIBA
01/2012
1Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2012
1Antimalarials (Antimalarial Agents)IBA
12/2011
1IronIBA
12/2011
1WortmanninIBA
09/2010
14- (2- (dimethylamino)vinyl)- 2- (3- hydroxyphenyl)- 6- morpholinopyrimidine- 5- carbonitrileIBA
09/2010

Therapy/Procedure

2Therapeutics
04/2012 - 09/2010
1Herniorrhaphy
01/2020
1Sutures (Suture)
01/2020